Altay C, Huisman T H, Schroeder W A
Hemoglobin. 1976;1(2):125-33. doi: 10.3109/03630267608991675.
The propositus in a Black family has elevated Hb-F and approximately equal amounts of Hb-A and Hb-S. Hematological and chemical studies of the propositus and his family show elevated Hb-F in the father and a sibling and sickle cell trait in the mother and another sibling. This family is believed to have a form of the hereditary persistence of fetal hemoglobin in which beta chains are produced in cis to the determinant.
一个黑人家庭中的先证者血红蛋白F升高,血红蛋白A和血红蛋白S含量大致相等。对先证者及其家族的血液学和化学研究显示,父亲和一个兄弟姐妹的血红蛋白F升高,母亲和另一个兄弟姐妹有镰状细胞性状。据信,这个家族有一种胎儿血红蛋白遗传性持续存在的形式,其中β链在与决定因素顺式排列的情况下产生。