Dung T Z, Liu A H
Division of Periodontology, Yang-Ming University, Taipai, Taiwan.
Oral Dis. 1999 Apr;5(2):92-9. doi: 10.1111/j.1601-0825.1999.tb00071.x.
Human dentin has a higher content of organic matrix and more non-ideal hydroxyapatite than human enamel. Ultrastructural studies indicate that root caries involves both mineral dissolution and breakdown of the organic matrix. Factors involved in the root caries process seem more complicated than those in enamel caries. Moreover, the distinct roles of acids and enzymes and the sequence of events in the root caries process are not well-understood. Although Streptococcus mutans and Actinomyces viscosus are considered to be major pathogenic micro-organisms of root caries, their roles in degradation of the organic matrix components of root dentin need clarification. The purpose of this paper is to review the basic composition of root dentin and the roles of acids and both endogenous and bacterial enzymes in the root caries process.
与人类牙釉质相比,人类牙本质具有更高含量的有机基质和更多不理想的羟基磷灰石。超微结构研究表明,根龋涉及矿物质溶解和有机基质的分解。参与根龋过程的因素似乎比釉质龋中的因素更为复杂。此外,酸和酶的独特作用以及根龋过程中事件的顺序尚未得到充分理解。虽然变形链球菌和粘性放线菌被认为是根龋的主要致病微生物,但它们在根牙本质有机基质成分降解中的作用需要阐明。本文的目的是综述根牙本质的基本组成以及酸、内源性酶和细菌酶在根龋过程中的作用。