Fatihi E, Zahiri K, Hachim K, Fadel H, Benghanem G M, Sqalli S, Ramdani B, Zaïd D
Service de néphrologie-hémodialyse, CHU Ibn Rochd, Casablanca, Maroc.
Rev Med Interne. 1999 Sep;20(9):759-61. doi: 10.1016/s0248-8663(00)88681-6.
To assess the value of accessory salivary gland biopsy for the diagnosis of amyloidosis, a study was conducted in the nephrology and hemodialysis department at Ibn Rochd University Hospital from February 1996 to January 1998.
Renal amyloidosis was confirmed by renal biopsy accompanying accessory salivary gland biopsy.
The patient's mean age was 39 years old (range 15-80), with a 4:1-male/female ratio. An infectious cause (either tuberculosis or superinfection and dilatation of the bronchi) was the most frequent (70% of the cases) etiology. All the patients presented renal symptomatology. Nephrotic syndrome predominated. Amyloid deposits were observed in 100% of renal needle biopsies and in 80% of accessory salivary gland biopsies.
Renal biopsy led to more positive cases than the other biopsies. It may be accompanied by severe complications. Furthermore, biopsy of the accessory salivary glands is a simple and very reliable technique for the diagnosis of amyloidosis. It is currently the best diagnostic test.
为评估副唾液腺活检对淀粉样变性诊断的价值，于1996年2月至1998年1月在伊本·鲁世德大学医院肾病与血液透析科开展了一项研究。
通过肾活检并同时进行副唾液腺活检来确诊肾淀粉样变性。
患者的平均年龄为39岁（范围15 - 80岁），男女比例为4:1。感染性病因（结核病或支气管的重复感染及扩张）是最常见的病因（占病例的70%）。所有患者均有肾脏症状。以肾病综合征为主。在100%的肾穿刺活检和80%的副唾液腺活检中观察到淀粉样沉积物。
肾活检比其他活检的阳性病例更多。它可能伴有严重并发症。此外，副唾液腺活检是诊断淀粉样变性的一种简单且非常可靠的技术。它是目前最佳的诊断检测方法。
