HLA-DQ1 associated with reflex sympathetic dystrophy.
作者信息
Kemler M A, van de Vusse A C, van den Berg-Loonen E M, Barendse G A, van Kleef M, Weber W E
机构信息
Department of Surgery, Maastricht University Hospital, The Netherlands.
出版信息
Neurology. 1999 Oct 12;53(6):1350-1. doi: 10.1212/wnl.53.6.1350.
PMID:10522900
Abstract
Reflex sympathetic dystrophy (RSD) is a relatively common disabling disorder of unknown pathophysiology. From a cohort of 52 patients, carefully selected to fulfill the recently formulated diagnostic criteria for RSD, venous blood samples were taken for typing of class I and II major histocompatibility antigens. The frequency of HLA-DQ1 was found to be significantly increased compared with control frequencies. The association provides an indication for an organic basis of RSD.
摘要
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