Massion J
Appl Neurophysiol. 1976;39(3-4):222-38. doi: 10.1159/000102498.
The ventrolateral (VL) and anterior (VA) are the main thalamic relay for cerebellar and pallidal efferents going to the motor cortex. Four aspects of the function of these nuclei are briefly considered. (1) It is well known that these thalamic structures are not a simple relay on the way to the motor cortex, but that they have a gating function for the cerebellar afferents. The gating mechanism is active during slow-wave sleep, with deafferentation and with the use of various anesthetics. Possibly, it might play a role in the central organization of movement. (2) The organization at the unitary level of the projections between VL and motor cortex is examined and their role in the command of motor synergies through the motor cortex is strongly suggested. (3). It appears that unitary activity of VL neurons is not only related to movement but also to postural changes associated with movement. (4) The sensory input to VL nucleus is briefly analyzed. The inefficacy of exteroceptive stimulation in awake animals, in contrast with the effect of the same stimulation in anesthetized preparations, is discussed.
腹外侧核(VL)和腹前核(VA)是小脑和苍白球传出纤维至运动皮层的主要丘脑中继站。简要考虑了这些核团功能的四个方面。(1)众所周知,这些丘脑结构并非通往运动皮层途中的简单中继站,而是对小脑传入纤维具有门控功能。该门控机制在慢波睡眠期间、传入神经阻滞时以及使用各种麻醉剂时均有活性。它可能在运动的中枢组织中发挥作用。(2)研究了VL与运动皮层之间投射在单一水平上的组织,并强烈提示它们在通过运动皮层指挥运动协同作用中的作用。(3)似乎VL神经元的单一活动不仅与运动有关,还与运动相关的姿势变化有关。(4)简要分析了VL核的感觉输入。讨论了清醒动物中外感受性刺激无效,与麻醉制剂中相同刺激的效果形成对比。