Phillips J B, Beens J
Department of Chemistry and Biochemistry, Southern Illinois University at Carbondale 62901-4409, USA.
J Chromatogr A. 1999 Sep 24;856(1-2):331-47. doi: 10.1016/s0021-9673(99)00815-8.
Comprehensive two-dimensional gas chromatography (GC x GC) provides a true orthogonal separation system. It is explained and demonstrated that it generates a peak capacity that is approximately equal to the product of the peak capacities of the two individual separation systems. The resulting peaks are ordered in a two-dimensional plane in bands of compounds with the same characteristics. Quantitation of the separated (groups of) components is fundamentally not different from one-dimensional gas chromatography, but the sensitivity is far better and true baseline is always available. The two co-ordinates of each peak in the plane make the identification more reliable. Instrumental considerations of GC x GC are discussed. The three designs of contemporary GC x GC systems are presented and compared. Although the technique is still very young, a number of applications on complex samples as petroleum and environmental samples have already been reported. Finally, the future perspectives of GC x GC are discussed.
全二维气相色谱（GC×GC）提供了一种真正的正交分离系统。文中解释并论证了它所产生的峰容量大约等于两个独立分离系统峰容量的乘积。所得峰在二维平面中按具有相同特征的化合物带进行排列。分离出的（组）组分的定量从根本上来说与一维气相色谱并无不同，但灵敏度要好得多，并且始终可以获得真正的基线。平面中每个峰的两个坐标使鉴定更加可靠。讨论了GC×GC的仪器相关考虑因素。介绍并比较了当代GC×GC系统的三种设计。尽管该技术仍非常年轻，但已经报道了在石油和环境样品等复杂样品上的一些应用。最后，讨论了GC×GC的未来前景。
