Delpino A, Ferrini U
Arch Sci Biol (Bologna). 1976 Jan-Dec;60(1-4):49-58.
Ribosomal subunits, isolated from mouse liver after a single dose of 50 mg/Kg b. w. of DMN, have been tested for their structural and functional properties. CsCl analysis has shown that after DMN treatment no loss of structural proteins occurs in both 40 S and 60 S ribosome subunits. It has been also demonstrated that these subunits are able to synthetize in the poly-U programmed system at low Mg++ concentrations, in the presence of heterologous initiation factors, at the same efficiency as the corresponding controls.
从单次给予50毫克/千克体重二甲基亚硝胺（DMN）后的小鼠肝脏中分离出的核糖体亚基，已对其结构和功能特性进行了测试。氯化铯分析表明，DMN处理后，40S和60S核糖体亚基中均未发生结构蛋白的丢失。还已证明，在低镁离子浓度下，在存在异源起始因子的情况下，这些亚基能够在聚尿苷酸（poly-U）编程系统中以与相应对照相同的效率进行合成。
