Otto H H, Buchali K, Krause E G
Z Exp Chir. 1975;8(3):160-7.
After establishing a model of ischemia, perfusion in the ischemic area was considerably disturbed. Examination by means of 133xenon-clearance after intramyocardiac injection showed strongly delayed flowing-off compared with controls. Counterpulsation accelerates the flowing-off (perfusion). Untreated control animals reveal after inducing the model ischemia a crucial decrease of ATP concentration and an excessive increase of lactate concentration in the ischemic area. Counterpulsation may inhibit further decrease of ATP in the ischemic area.
建立缺血模型后,缺血区域的灌注受到严重干扰。心肌内注射后通过133氙清除法检查发现,与对照组相比,血流流出明显延迟。反搏可加速血流流出(灌注)。未治疗的对照动物在诱导模型缺血后,缺血区域的ATP浓度显著降低,乳酸浓度过度升高。反搏可抑制缺血区域ATP的进一步降低。