Sagawa M, Sato M, Fujimura S, Sakurada A, Takahashi H, Kondo T, Endo C, Tanita T, Ono S, Saito Y
Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
J Cardiovasc Surg (Torino). 1999 Aug;40(4):603-5.
Patients having malignant chest diseases sometimes suffer from vocal fold paralysis. Treatment for vocal fold paralysis is important for such patients, because vocal fold paralysis causes lack of the versatility of the human voice which is essential for our communication.
Seventeen patients suffering from unilateral vocal fold paralysis were treated with vocal fold injections of collagen. Three patients received twice, and 20 treatments were conducted. A flexible bronchofiberscope was used under local anesthesia in order to observe the whole procedure of vocal fold injection. Using an injector and a long needle, collagen was injected with transcutaneous technique mainly through the cricothyroid membrane. The amount of collagen was determined with bronchoscopic findings.
During and after treatment, no complication was observed. Of 20 treatments, a marked improvement was observed in 8, and moderate improvement was observed in 9 treatments.
Vocal fold injection of collagen is a very useful and safe treatment for unilateral vocal fold paralysis caused by chest diseases.
患有恶性胸部疾病的患者有时会出现声带麻痹。声带麻痹的治疗对这类患者很重要，因为声带麻痹会导致人类声音缺乏多样性，而声音多样性对我们的交流至关重要。
17例单侧声带麻痹患者接受了声带胶原蛋白注射治疗。3例患者接受了两次注射，共进行了20次治疗。在局部麻醉下使用可弯曲支气管纤维镜观察声带注射的全过程。使用注射器和长针，主要通过环甲膜采用经皮技术注射胶原蛋白。根据支气管镜检查结果确定胶原蛋白的用量。
治疗期间及治疗后均未观察到并发症。在20次治疗中，8次观察到明显改善，9次观察到中度改善。
声带注射胶原蛋白是治疗胸部疾病引起的单侧声带麻痹非常有用且安全的方法。
