Choi J, Son Y-I, So Y K, Byun H, Lee E-K, Yun Y-S
Department of Otorhinolaryngology - Head and Neck Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, South Korea.
J Laryngol Otol. 2012 Mar;126(3):260-6. doi: 10.1017/S0022215111002702. Epub 2011 Oct 6.
This study aimed to analyse demographic profiles and pre-injection stroboscopic findings for patients with unilateral vocal fold paralysis, to investigate possible predictive factors for voice outcomes of injection laryngoplasty.
Fifty-nine unilateral vocal fold paralysis patients underwent vocal fold augmentation, using transcutaneous Artecoll (polymethyl methacrylate microspheres plus bovine collagen) injection into the paralysed vocal fold via the cricothyroid space. Three months later, patients were divided into improved (n = 44) and unimproved (n = 15) groups, using the perceptual grade-roughness-breathiness-asthenia-strain scale, and their clinical characteristics and pre-operative stroboscopic findings compared.
The improved group were significantly younger than the unimproved group (p = 0.000). The size of the posterior gap on phonation was closely associated with the outcome of injection laryngoplasty (p = 0.015).
Younger patients with a smaller posterior glottic gap on phonation can be expected to have a more favourable outcome following injection laryngoplasty for correction of glottic insufficiency due to unilateral vocal fold paralysis.
本研究旨在分析单侧声带麻痹患者的人口统计学特征及注射前频闪喉镜检查结果,以探究注射喉成形术语音预后的可能预测因素。
59名单侧声带麻痹患者接受了声带增强术,通过环甲膜间隙将经皮注射用Artecoll(聚甲基丙烯酸甲酯微球加牛胶原蛋白)注入麻痹的声带。三个月后,使用感知粗糙度-呼吸音-无力-紧张量表将患者分为改善组(n = 44)和未改善组(n = 15),并比较他们的临床特征和术前频闪喉镜检查结果。
改善组患者明显比未改善组患者年轻(p = 0.000)。发声时后间隙的大小与注射喉成形术的结果密切相关(p = 0.015)。
发声时声门后间隙较小的年轻患者,在接受注射喉成形术以纠正单侧声带麻痹所致声门闭合不全后,有望获得更良好的预后。