Walker M F, Zee D S
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Neurology. 1999 Oct 22;53(7):1576-9. doi: 10.1212/wnl.53.7.1576.
Hyperventilation can affect nystagmus in patients with vestibular disorders. However, the effects on nystagmus in patients with cerebellar disease have not been systematically studied. Using the magnetic field search coil technique, we studied the effects of hyperventilation on nystagmus in a series of cerebellar patients. In four of eight patients, hyperventilation produced an increase in the slow-phase velocity of downbeat nystagmus. We speculate that this effect may be mediated through metabolic effects on cerebellar calcium channels.
过度通气可影响前庭疾病患者的眼球震颤。然而，其对小脑疾病患者眼球震颤的影响尚未得到系统研究。我们使用磁场搜索线圈技术，研究了过度通气对一系列小脑疾病患者眼球震颤的影响。在8名患者中的4名患者中，过度通气使下跳性眼球震颤的慢相速度增加。我们推测这种效应可能是通过对小脑钙通道的代谢作用介导的。
