Miller R J, Davey R B, George J E
Knipling-Bushland U.S. Livestock Insects Laboratory, USDA-ARS, Kerrville, TX 78028-9184, USA.
J Med Entomol. 1999 Sep;36(5):533-8. doi: 10.1093/jmedent/36.5.533.
Two patterns of pyrethroid resistance were characterized from Boophilus microplus (Canestrini) collected in Mexico. One was characteristic of a kdr mutation and the other involved esterase and cytochrome P450 enzyme systems. Very high resistance to permethrin, cypermethrin, and flumethrin, not synergized by TPP and PBO and high resistance to DDT, characterized the kdr-like pattern found in the Corrales and San Felipe strains. Esterase and cytochrome P450-dependent resistance was found in the Coatzacoalcos strain. It was characterized by resistance to permethrin, cypermethrin, and flumethrin, synergized by TPP and PBO, but no resistance to DDT. The Coatzacoalcos strain also showed 3.6-fold resistance to the organophosphate coumaphos. This factor appeared to be independent of pyrethroid resistance. Pyrethroid resistance patterns found in Mexico were similar to those found earlier in Australia. The significance of pyrethroid and coumaphos resistance to the U.S. cattle fever tick quarantine is discussed.
从墨西哥采集的微小牛蜱（Canestrini）中鉴定出两种拟除虫菊酯抗性模式。一种是kdr突变的特征，另一种涉及酯酶和细胞色素P450酶系统。对氯菊酯、氯氰菊酯和氟氯氰菊酯具有极高抗性，不受三苯基磷酸酯（TPP）和胡椒基丁醚（PBO）增效，且对滴滴涕具有高抗性，这是在科拉莱斯和圣费利佩菌株中发现的类似kdr模式的特征。在科阿特萨科科斯菌株中发现了酯酶和细胞色素P450依赖性抗性。其特征是对氯菊酯、氯氰菊酯和氟氯氰菊酯具有抗性，可被TPP和PBO增效，但对滴滴涕无抗性。科阿特萨科科斯菌株对有机磷化合物蝇毒磷也表现出3.6倍的抗性。该因素似乎与拟除虫菊酯抗性无关。在墨西哥发现的拟除虫菊酯抗性模式与之前在澳大利亚发现的相似。讨论了拟除虫菊酯和蝇毒磷抗性对美国牛蜱检疫的意义。
