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[新生儿肾横纹肌样瘤:1例超微结构观察病例报告]

[Rhabdoid tumor of the kidney arising in a newborn infant: description of a case with ultrastructural observations].

作者信息

Terlizzo M, Ambu R, Crisponi G, Marras A, Faa G

机构信息

Dipartimento di Citomorfologia, Università di Cagliari.

出版信息

Pathologica. 1999 Jun;91(3):198-202.

Abstract

INTRODUCTION

Rhabdoid tumour of the kidney is a new independent entity. Before it was considered a variant of Wilms tumor of the kidney. Now we have enough parametres to define the rhabdoid tumor: immunohistochemistry positive by the vimentin, special histological features and behaviour.

CASE

We report a very aggressive case of rhabdoid tumor found in a two week old infant.

RESULTS

We studied aspects of histology and histochemistry. We found a positivity for vimentin and many cells in apoptosis.

DISCUSSION

The mild positivity for vimentin and the high number of cells in apoptosis suggest a relationship between apoptosis and behaviour.

摘要

引言

肾横纹肌样瘤是一种新的独立实体。以前它被认为是肾母细胞瘤的一种变体。现在我们有足够的参数来定义横纹肌样瘤:波形蛋白免疫组化阳性、特殊的组织学特征及行为表现。

病例

我们报告了一例在一名两周大婴儿中发现的侵袭性很强的横纹肌样瘤病例。

结果

我们研究了组织学和组织化学方面。我们发现波形蛋白呈阳性,且有许多细胞处于凋亡状态。

讨论

波形蛋白轻度阳性以及大量凋亡细胞提示凋亡与行为之间存在关联。

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