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通过植入式泵持续鞘内注射巴氯芬治疗脑源性痉挛:18例患者的长期随访回顾

Treatment of cerebral origin spasticity with continuous intrathecal baclofen delivered via an implantable pump: long-term follow-up review of 18 patients.

作者信息

Rawicki B

机构信息

Acute Rehabilitation, Southern Healthcare Network, Hampton Rehabilitation Hospital, Victoria, Australia.

出版信息

J Neurosurg. 1999 Nov;91(5):733-6. doi: 10.3171/jns.1999.91.5.0733.

Abstract

OBJECT

The goal of this study was to assess the long-term benefits of managing severe spasticity by using continuous infusion of intrathecal baclofen delivered via an implantable pump.

METHODS

Eighteen patients with severe spasticity of cerebral origin, who failed to respond adequately to more conservative treatments, have-been treated with continuous infusion of intrathecal baclofen delivered via an implanted pump. Follow-up review of these patients has lasted between 12 months and 9 years. The patients have been assessed using a variety of tools. Seventeen have had a significant reduction in tone and all have benefited by a reduced need for nursing care or increased function or both.

CONCLUSION

Long-term continuous infusion of intrathecal baclofen delivered via an implantable pump offers an effective method for dealing with otherwise intractable spasticity.

摘要

目的

本研究的目的是评估通过植入式泵持续输注鞘内巴氯芬来治疗严重痉挛的长期益处。

方法

18例脑源性严重痉挛患者,对更保守的治疗反应不佳,接受了通过植入式泵持续输注鞘内巴氯芬的治疗。对这些患者的随访持续了12个月至9年。使用多种工具对患者进行了评估。17例患者的肌张力有显著降低,所有患者都因护理需求减少、功能增强或两者兼而有之而受益。

结论

通过植入式泵长期持续输注鞘内巴氯芬为治疗其他方法难以处理的痉挛提供了一种有效方法。

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