氢化酶体：真核生物对厌氧环境的适应性结构

Hydrogenosomes: eukaryotic adaptations to anaerobic environments.

作者信息

Hackstein J H, Akhmanova A, Boxma B, Harhangi H R, Voncken F G

机构信息

Dept. of Microbiology and Evolutionary Biology, University of Nijmegen, Toernooiveld 1, NL-6525 ED Nijmegen, The Netherlands.

出版信息

Trends Microbiol. 1999 Nov;7(11):441-7. doi: 10.1016/s0966-842x(99)01613-3.

DOI:10.1016/s0966-842x(99)01613-3

PMID:10542423

Abstract

Like mitochondria, hydrogenosomes compartmentalize crucial steps of eukaryotic energy metabolism; however, this compartmentalization differs substantially between mitochondriate aerobes and hydrogenosome-containing anaerobes. Because hydrogenosomes have arisen independently in different lineages of eukaryotic microorganisms, comparative analysis of the various types of hydrogenosomes can provide insights into the functional and evolutionary aspects of compartmentalized energy metabolism in unicellular eukaryotes.

摘要

与线粒体一样，氢化酶体将真核生物能量代谢的关键步骤分隔开来；然而，这种分隔在含线粒体的需氧生物和含氢化酶体的厌氧生物之间存在很大差异。由于氢化酶体在不同的真核微生物谱系中独立出现，对各种类型氢化酶体的比较分析可以深入了解单细胞真核生物中能量代谢分隔的功能和进化方面。