Vögtli W, Nagel G A, Bianchi L, Truog P
Schweiz Med Wochenschr. 1975 Jan 4;105(1):27-8.
Report on a 74-year-old patient who developed acute myeloid leukemia 16 months after diagnosis of IgA paraproteinemia. He had received a total dose of 1.4-1.5 g melphalan. The possible etiologic role of melphalan in the development of acute leukemia is discussed.
关于一名74岁患者的报告,该患者在诊断为IgA副蛋白血症16个月后发生急性髓系白血病。他接受了总量为1.4 - 1.5克的美法仑。讨论了美法仑在急性白血病发生中的可能病因作用。