多发性骨髓瘤与终末期急性髓系白血病（作者译）
[Multiple myeloma and terminal acute myeloid leukaemia (author's transl)].
作者信息
Labedzki L, Fuchs H J, Grips K H
出版信息
Dtsch Med Wochenschr. 1976 Jan 23;101(4):108-11. doi: 10.1055/s-0028-1104045.
A patient with multiple myeloma died of an acute myeloid leukaemia 15 years after onset of the former. At time of diagnosis the 39 year-old-patient had bone marrow infiltration of maximally 32 plasma cells/100 white bone marrow cells, a paraprotein (IgG, light-chain type lambda), osteoporosis of late onset and occasional osteolysis. The long survival time, as well as the acute myeloid leukaemia, are probably due to the effective treatment, first with cyclophosphamide (198 g over four years), later melphalan (3000 mg over eight years).
一名多发性骨髓瘤患者在该病发病15年后死于急性髓系白血病。诊断时，这位39岁的患者骨髓浸润程度最高为每100个骨髓白细胞中有32个浆细胞，存在副蛋白（IgG，λ轻链型）、迟发性骨质疏松和偶尔的骨质溶解。较长的生存时间以及急性髓系白血病可能归因于有效的治疗，最初使用环磷酰胺（四年内共198克），后来使用美法仑（八年内共3000毫克）。
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