Ansseau M
Service de Psychiatrie et Psychologie médicale, Université de Liège.
Rev Med Liege. 1999 Aug;54(8):705-6.
Zaleplon (Sonata) is an original hypnotic derived from the pyrazolopyrimidine with a full agonistic activity on central benzodiazepine receptors B21 type. Zaleplon is characterized by an extremely short half-life (about 1 hour). At the 10 mg dose, it is an affective sleep inducer with limited risks of disturbances in morning performance. It is particularly suitable for the treatment of initial insomnia when the prescription of an hypnotic is justified.
扎来普隆（索纳塔）是一种源自吡唑并嘧啶的新型催眠药，对中枢苯二氮䓬B21型受体具有完全激动活性。扎来普隆的特点是半衰期极短（约1小时）。在10毫克剂量时，它是一种有效的睡眠诱导剂，对早晨的行为影响风险有限。当有合理理由开具催眠药处方时，它特别适用于治疗原发性失眠。
