Sparey C, Haddad N, Sissons G, Rosser S, de Cossart L
The Countess of Chester NHS Trust Hospital, Liverpool Road, Chester, CH2 1BQ, U.K.
Eur J Vasc Endovasc Surg. 1999 Oct;18(4):294-9. doi: 10.1053/ejvs.1999.0870.
to assess the effect of pregnancy on the lower-limb venous system of women with varicose veins. Design a longitudinal prospective study of 11 pregnant women, with varicose vein disease.
eleven pregnant women with varicose veins were recruited as part of a larger study. Veins were assessed in both lower limbs using colour-flow duplex scanning at a 75 degrees head-up tilt. The diameter and velocity and duration of reflux were measured in each vein at 12, 20, 26, 34, 38 weeks gestation and 6 weeks postpartum.
eleven women had reflux and varicose veins demonstrated at first scan. All veins dilated with increasing gestation. This was maximal in the superficial system, reaching significance (p</=0.05) in the right long saphenous, superficial femoral and posterior tibial veins, left long and short saphenous, popliteal, peroneal, anterior and posterior tibial veins. The velocity of reflux increased while the duration decreased with increasing gestation. This was most obvious in the long saphenous veins but did not reach statistical significance.
maximum changes were seen in the superficial venous system in the thigh. The effect was more pronounced on the left and the changes in reflux returned to pre-pregnancy levels in the puerperium.
评估妊娠对患有静脉曲张的女性下肢静脉系统的影响。设计一项针对11名患有静脉曲张疾病的孕妇的纵向前瞻性研究。
招募11名患有静脉曲张的孕妇作为一项更大规模研究的一部分。在75度头高位倾斜状态下,使用彩色血流双功扫描对双下肢静脉进行评估。在妊娠12、20、26、34、38周以及产后6周时,测量每条静脉的直径、反流速度和持续时间。
首次扫描时,11名女性均有反流和静脉曲张表现。随着孕周增加,所有静脉均扩张。在浅静脉系统中这种扩张最为明显,在右侧大隐静脉、股浅静脉和胫后静脉、左侧大隐静脉和小隐静脉、腘静脉、腓静脉、胫前静脉和胫后静脉中达到显著水平(p≤0.05)。随着孕周增加,反流速度增加而持续时间缩短。这在大隐静脉中最为明显,但未达到统计学意义。
大腿部浅静脉系统出现最大变化。这种影响在左侧更为明显,且产后反流变化恢复到妊娠前水平。