Breier J I, Simos P G, Zouridakis G, Papanicolaou A C
University of Texas Health Science Center, Department of Neurosurgery Houston, TX, USA.
J Clin Exp Neuropsychol. 1999 Aug;21(4):465-76. doi: 10.1076/jcen.21.4.465.883.
Spatiotemporal maps of brain activity were obtained from nine normal volunteers engaged in a pseudoword rhyme-matching task using Magnetic Source Imaging. Following bilateral occipital activity there was a clear temporal progression of activity in the left hemisphere beginning with basal temporal areas followed closely by activity in the angular gyrus and inferior frontal lobe. Medial temporal and posterior superior temporal lobe became active last. There was a strong interhemispheric asymmetry in activity favoring the left hemisphere in all areas. A control, pattern-matching task, with no verbal demands, exhibited a different spatiotemporal pattern of activity. These results agree anatomically with previous studies in other imaging modalities. In addition, the relative timing of activity in basal temporal areas of the left hemisphere supports hypotheses regarding a role for this area in early processing of visually presented verbal material.
利用磁源成像技术，从九名参与假词押韵匹配任务的正常志愿者身上获取了大脑活动的时空图谱。双侧枕叶活动之后，左半球出现了明显的活动时间进程，始于颞叶基部区域，紧接着角回和额下回也出现活动。颞叶内侧和颞上叶后部最后变得活跃。所有区域的活动都存在强烈的半球间不对称，左半球更为活跃。一项无言语要求的对照模式匹配任务表现出不同的时空活动模式。这些结果在解剖学上与之前其他成像方式的研究一致。此外，左半球颞叶基部区域活动的相对时间支持了关于该区域在视觉呈现的语言材料早期处理中作用的假设。
