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精神病患者的语义和情感加工:一项事件相关电位(ERP)研究。

Semantic and affective processing in psychopaths: an event-related potential (ERP) study.

作者信息

Kiehl K A, Hare R D, McDonald J J, Brink J

机构信息

Department of Psychology, University of British Columbia, Vancouver, Canada.

出版信息

Psychophysiology. 1999 Nov;36(6):765-74.

PMID:10554590
Abstract

We tested the hypothesis that psychopathy is associated with abnormal processing of semantic and affective verbal information. In Task 1, a lexical decision task, and in Task 2, a word identification task, participants responded faster to concrete than to abstract words. In Task 2, psychopaths made more errors identifying abstract words than concrete words. In Task 3, a word identification task, participants responded faster to positive than to negative words. In all three tasks, nonpsychopaths showed the expected event-related potential (ERP) differentiation between word stimuli, whereas psychopaths did not. In each task, the ERPs of the psychopaths included a large centrofrontal negative-going wave (N350); this wave was absent or very small in the nonpsychopaths. The interpretation and significance of these differences are discussed.

摘要

我们检验了这样一个假设

心理变态与语义和情感语言信息的异常处理有关。在任务1(词汇判断任务)和任务2(单词识别任务)中,参与者对具体词汇的反应比对抽象词汇的反应更快。在任务2中,心理变态者在识别抽象词汇时比识别具体词汇时犯的错误更多。在任务3(单词识别任务)中,参与者对积极词汇的反应比对消极词汇的反应更快。在所有这三项任务中,非心理变态者在单词刺激之间表现出预期的事件相关电位(ERP)差异,而心理变态者则没有。在每项任务中,心理变态者的ERP都包含一个大的中央额叶负向波(N350);在非心理变态者中,这个波不存在或非常小。我们将讨论这些差异的解释和意义。

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