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Synthesis and antimicrobial activity of some new flavonyl oxime ether derivatives.

作者信息

Tunçbilek M, Bozdağ O, Ayhan-Kilcigil G, Altanlar N, Buyukbingol E, Ertan R

机构信息

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, Tandoğan, Turkey.

出版信息

Arzneimittelforschung. 1999 Oct;49(10):853-7. doi: 10.1055/s-0031-1300514.

Abstract

The synthesis of a series of 6 compounds related to 2-(4'-formyl-phenyl)-4]H-1-benzopyran-4-one O-substituted oxime and the results of a study of their biological activity are reported. The structural assignments of the compounds is based upon various spectral data. The prepared compounds were screened for their in vitro antibacterial and antifungal activities. Compound F3 exhibited the best antifungal activity compared with ketoconazole and fluconazole.

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