黄酮-3'-甲醛肟醚衍生物的合成及其抗菌活性
Synthesis and antimicrobial activity of flavone-3'-carboxaldehyde oxime ether derivatives.
作者信息
Bozdağ-Dündar Oya, Tunçbilek Meral, Altanlar Nurten, Ertan Rahmiye
机构信息
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, Ankara, Turkey.
出版信息
Arzneimittelforschung. 2003;53(7):522-5. doi: 10.1055/s-0031-1297143.
PMID:12918219
Abstract
A new series of flavonyl oxime ether derivatives (FO1-FO6) was prepared by reaction of flavone-3'-carboxaldehyde (III) with O-substituted hydroxyl amine derivatives (IV). The synthesized compounds were tested for their in vitro antifungal and antibacterial activities. All the compounds exhibited antimicrobial activity.
摘要
通过黄酮-3'-甲醛（III）与O-取代羟胺衍生物（IV）反应制备了一系列新的黄酮肟醚衍生物（FO1-FO6）。对合成的化合物进行了体外抗真菌和抗菌活性测试。所有化合物均表现出抗菌活性。
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