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某些金刚烷酮肟醚的合成、抗真菌、抗菌及抗病毒作用

Synthesis, antifungal, antibacterial and antiviral effects of some adamantaneketoxime ethers.

作者信息

Papadaki-Valiraki A, Papakonstantinou-Garoufalias S, Marakos P, Chytyroglou-Lada A, Hosoya M, Balzarini J, de Clercq E

机构信息

Department of Pharmaceutical Chemistry, University of Athens, Greece.

出版信息

Farmaco. 1993 Aug;48(8):1091-102.

PMID:8216671
Abstract

A number of adamantaneketoxime ethers and an acetylenic adamantaneketoxime iododerivative have been prepared and tested as potential antifungal agents. They were also examined for their antibacterial and antiviral effects. Most of them proved active against the tested fungi. Their antimicrobial activity was generally low, while they did not exhibit a "specific" antiviral activity against any of the viruses tested.

摘要

已经制备了多种金刚烷酮肟醚和一种炔基金刚烷酮肟碘衍生物,并作为潜在的抗真菌剂进行了测试。还对它们的抗菌和抗病毒作用进行了研究。其中大多数对测试的真菌具有活性。它们的抗菌活性一般较低,同时对所测试的任何病毒均未表现出“特异性”抗病毒活性。

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