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安提瓜和巴布达充血性心力衰竭的患病率、病因及治疗

The prevalence, aetiology and treatment of congestive cardiac failure in Antigua and Barbuda.

作者信息

McSwain M, Martin T C, Amaraswamy R

机构信息

Holberton Hospital, St John's, Antigua, WI.

出版信息

West Indian Med J. 1999 Sep;48(3):137-40.

Abstract

A retrospective review of the cases of congestive heart failure admitted to Holberton Hospital in Antigua in 1995 and 1996 was undertaken. Two hundred and ninety-three (293) patients were identified by International Statistical Classification of Diseases, 10th revision (ICD-10) coding as having congestive cardiac failure in the period but only 138 charts were either available or fitted the definition of congestive cardiac failure and these provided the basis for this analysis. The average age of patients admitted for congestive cardiac failure was 69 years (range: 5 months to 99 years), and 63% were female. the aetiology of congestive cardiac failure was hypertension (41%), ischaemia (33%), valvular (12%), alcohol related (2%), idiopathic (5%) and mixed (7%). Treatment included diuretics (95%), angiotensin converting enzyme inhibitors (78%), digoxin (75%), nitrates (34%), calcium channel blockers (25%), other vasodilators (7%) and antiarrhythmics (5%). Of those with congestive heart failure, diabetes was present in 38%, atrial fibrillation in 19%, renal insufficiency in 17%, elevated cholesterol in 11%, obesity in 9% and tobacco use in 7%. The in-hospital mortality in the 2-year period was 17.4% (females 15%, males 22%, 11% < 65 years, 20% > 65 years, 14% for those with 1 to 3 admissions and 83% for those with > 3 admissions, 19% for those with atrial fibrillation and 16% for those without). The prevalence of congestive cardiac failure utilizing the data analysed in this study (138 patients) was 0.21% of the population of the island state but based on the discharge diagnosis using ICD-10 coding it was 0.5%; it was 1% in the 40 to 65-year-age group and 4% in those > 65 years of age. The patients in this study represented only those with New York Heart Association (NYHA) classes III and IV, hence the true prevalence would be higher than recorded here. Congestive cardiac failure is emerging as a significant health problem in Antigua and Barbuda.

摘要

对1995年和1996年入住安提瓜岛霍尔伯顿医院的充血性心力衰竭病例进行了回顾性研究。根据国际疾病分类第10版(ICD - 10)编码,确定在此期间有293名患者患有充血性心力衰竭,但只有138份病历可供使用或符合充血性心力衰竭的定义,这些病历为本次分析提供了依据。因充血性心力衰竭入院的患者平均年龄为69岁(范围:5个月至99岁),63%为女性。充血性心力衰竭的病因包括高血压(41%)、缺血(33%)、瓣膜病(12%)、酒精相关(2%)、特发性(5%)和混合型(7%)。治疗方法包括利尿剂(95%)、血管紧张素转换酶抑制剂(78%)、地高辛(75%)、硝酸盐(34%)、钙通道阻滞剂(25%)、其他血管扩张剂(7%)和抗心律失常药(5%)。在患有充血性心力衰竭的患者中,38%患有糖尿病,19%患有心房颤动,17%患有肾功能不全,11%胆固醇升高,9%肥胖,7%吸烟。两年期间的住院死亡率为17.4%(女性15%,男性22%,65岁以下11%,65岁以上20%,入院1至3次的患者为14%,入院超过3次的患者为83%,患有心房颤动的患者为19%,未患心房颤动的患者为16%)。利用本研究分析的数据(138名患者),充血性心力衰竭的患病率为该岛国人口的0.21%,但根据ICD - 10编码的出院诊断,患病率为0.5%;在40至65岁年龄组中为1%,在65岁以上人群中为4%。本研究中的患者仅代表纽约心脏协会(NYHA)III级和IV级患者,因此实际患病率将高于此处记录。充血性心力衰竭正在成为安提瓜和巴布达一个重要的健康问题。

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