Adekanmbi A F, Ogunlesi T A, Olowu A O, Fetuga M B
Department of Paediatrics, Olabisi Onabanjo University, Sagamu, Nigeria.
J Trop Pediatr. 2007 Apr;53(2):103-6. doi: 10.1093/tropej/fml064. Epub 2006 Dec 13.
Congestive cardiac failure (CCF) is a common paediatric emergency with diverse aetiologies. The objective of this study is to define the current prevalence rate and common causes of CCF among children hospitalized in a Nigerian Tertiary Hospital. The study was prospectively done over a 1-year period in the Paediatric Wards of the hospital. Consecutive children aged 0-14 years, who fulfilled the standard diagnostic criteria for CCF were recruited. Data obtained from them included the age, sex, duration of illness and the socioeconomic status of the parents. Each subject was given a specific diagnosis based on the clinical, laboratory and radiological features. Out of a total of 1552 admissions, 109 had CCF giving the prevalence of 7.02%. The mean age of children with CCF was mean of 2 +/- 3.1 years (range: 1 day to 14 years). Ninety-five (91%) of them were concentrated in the lower socioeconomic classes III-V. The aetiologies of CCF identified in this study were as follows: severe anaemia occurring alone (48; 46%), lower respiratory tract infections (LRTI) (30; 29%), anaemia with LRTI (12; 11.5%), congenital heart diseases (CHD) (11; 10.5%), rheumatic heart disease (1; 1%), myocarditis (1; 1%) and chronic renal disease (1; 1%). Malaria was the commonest cause of anaemia while bronchopneumonia was the commonest form of LRTI in the subjects. Measles infection was associated with LRTI in 10 (23.8%) children. Three children had HIV-related anaemia. Infants formed the bulk of the subjects with CCF due to anaemia, LRTI and CHD. Ventricular septal defect was the commonest CHD identified. The prevalence obtained from this study was higher than rates obtained from some previous studies in the country. Severe anaemia is the commonest cause of CCF probably from the effects of severe malaria and increasing poverty. Stringent attention to poverty alleviation and malaria control may reduce the burden of CCF among Nigerian children.
充血性心力衰竭(CCF)是一种常见的儿科急症,病因多样。本研究的目的是确定尼日利亚一家三级医院住院儿童中CCF的当前患病率及常见病因。该研究在医院儿科病房前瞻性地进行了1年。招募了符合CCF标准诊断标准的0至14岁连续儿童。从他们那里获得的数据包括年龄、性别、病程以及父母的社会经济状况。根据临床、实验室和放射学特征对每个受试者进行特定诊断。在总共1552例入院病例中,109例患有CCF,患病率为7.02%。CCF患儿的平均年龄为2±3.1岁(范围:1天至14岁)。其中95例(91%)集中在社会经济较低的III - V类。本研究中确定的CCF病因如下:单纯严重贫血(48例;46%)、下呼吸道感染(LRTI)(30例;29%)、贫血合并LRTI(12例;11.5%)、先天性心脏病(CHD)(11例;10.5%)、风湿性心脏病(1例;1%)、心肌炎(1例;1%)和慢性肾病(1例;1%)。疟疾是贫血最常见的原因,而支气管肺炎是受试者中LRTI最常见的形式。10例(23.8%)儿童的麻疹感染与LRTI有关。3例儿童患有与HIV相关的贫血。由于贫血、LRTI和CHD,婴儿占CCF受试者的大部分。室间隔缺损是最常见的CHD类型。本研究获得的患病率高于该国此前一些研究的结果。严重贫血可能是由于严重疟疾的影响和贫困加剧,是CCF最常见的原因。严格关注扶贫和疟疾控制可能会减轻尼日利亚儿童CCF的负担。