Gu Z Y, Wu H L, Wu Q L, Cao Z Q, Zhang Y X
Department of Stomatology, First Teaching Hospital, Zhejiang Medical University (ZMU), P. R. China.
Chin J Dent Res. 1998 Dec;1(3):44-8.
To investigate the effect of intra-articular irrigation-injection therapy in treating osteoarthrosis of the temporomandibular joint.
Thirty-seven patients (the test group) received intra-articular irrigation injection; 26 patients (the control group) received intra-articular injection of steroid. The synovial fluid, aspirated from five subjects of the test group before and after the therapy, was assayed to determine the tumor necrosis factor.
Clinical evaluations were performed 3 months after the therapy. Thirteen subjects in the test group fell into the "excellent" category, 19 into the "good" category, and five into the "no effect" category; in the control group, eight subjects fell into the "excellent" category; nine into the "good" category, and nine into the "no effect" category. The category difference in total effectiveness between the test group and the control group is statistically significant (X2 = 3.9340 P < 0.05). TNF in synovial fluid also showed statistically significant differences before and after treatment (T = 2.8825, P < 0.05).
Intra-articular irrigation injection is an effective therapy method for treating osteoarthrosis and is superior to intra-articular injection of steroid.
探讨关节腔内冲洗注射疗法治疗颞下颌关节骨关节炎的效果。
37例患者(试验组)接受关节腔内冲洗注射;26例患者(对照组)接受关节腔内注射类固醇。对试验组5例患者治疗前后抽取的滑液进行检测以测定肿瘤坏死因子。
治疗3个月后进行临床评估。试验组13例患者为“优”,19例为“良”,5例为“无效”;对照组8例患者为“优”,9例为“良”,9例为“无效”。试验组与对照组总有效率的类别差异具有统计学意义(X2 = 3.9340,P < 0.05)。滑液中的肿瘤坏死因子治疗前后也显示出统计学意义上的差异(T = 2.8825,P < 0.05)。
关节腔内冲洗注射是治疗骨关节炎的一种有效治疗方法,且优于关节腔内注射类固醇。