Zhou X D, Hu T, Zhang P, Tan H
College of Stomatology, West China University of Medical Sciences, Chengdu, P. R. China.
Chin J Dent Res. 1998 Sep;1(2):37-40.
This study investigated the biosynthesis of P-aminobenzoic acid by Streptococcus sanguis and the role of P-aminobenzoic acid in the interaction between Streptococcus sanguis and Streptococcus mutans.
A reversed-phase high-performance liquid chromatographic technique was used to analyze the P-aminobenzoic acid synthesized by Streptococcus sanguis in an anaerobic atmosphere.
The results showed, that (1) the chromatographic method established in this study had good linear relation and the average recovery of P-aminobenzoic acid was 80%, and (2) Streptococcus sanguis did synthesize P-aminobenzoic acid, and the mean concentration of P-aminobenzoic acid was 1.23 micrograms/mL.
The results of this study will help further studies of the factors that may have effects on P-aminobenzoic acid synthesis by Streptococcus sanguis and on the role of P-aminobenzoic acid in the microbial homeostasis of dental plaque.
本研究调查了血链球菌对对氨基苯甲酸的生物合成以及对氨基苯甲酸在血链球菌与变形链球菌相互作用中的作用。
采用反相高效液相色谱技术分析血链球菌在厌氧环境中合成的对氨基苯甲酸。
结果显示，（1）本研究建立的色谱方法具有良好的线性关系，对氨基苯甲酸的平均回收率为80%，（2）血链球菌确实能合成对氨基苯甲酸，其平均浓度为1.23微克/毫升。
本研究结果将有助于进一步研究可能影响血链球菌对氨基苯甲酸合成的因素以及对氨基苯甲酸在牙菌斑微生物稳态中的作用。
