Maltz-Turkienicz M, Krasse B, Emilson C G
Scand J Dent Res. 1980 Feb;88(1):28-33. doi: 10.1111/j.1600-0722.1980.tb00716.x.
Both chlorhexidine and iodine showed greater antimicrobial effect on in vitro grown S. mutans plaque than on plaque composed of S. sanguis. One treatment with iodine for 8 min inhibited the acid production of S. Mutans plaque whereas S. sanguis plaque required 20 min to be similarly affected. In contrast one treatment with chlorhexidine for up to 20 min did not completely inhibit the acid production of plaque of either microorganism. Repeated short term exposures increased the bactericidal effect of chlorhexidine but not that of iodine. The difference in antimicrobial effect between chlorhexidine and that of iodine on S. mutans and S. sanguis should be investigated in persons heavily infected by S. mutans.
洗必泰和碘对体外培养的变形链球菌菌斑的抗菌作用均强于对血链球菌组成的菌斑。用碘处理8分钟可抑制变形链球菌菌斑产酸，而血链球菌菌斑需20分钟才会受到类似影响。相比之下，用洗必泰处理长达20分钟并未完全抑制这两种微生物菌斑的产酸。反复短期接触可增强洗必泰的杀菌效果，但碘的杀菌效果并未增强。对于变形链球菌严重感染的人群，应研究洗必泰和碘对变形链球菌和血链球菌抗菌作用的差异。
