Antonio M A, Hawes S E, Hillier S L
Magee-Womens Research Institute, Department of Obstetrics, Gynecology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
J Infect Dis. 1999 Dec;180(6):1950-6. doi: 10.1086/315109.
Lactobacillus acidophilus has been reported to be the predominant vaginal species. Vaginal lactobacilli isolated from 215 sexually active women were identified using whole-chromosomal DNA probes to 20 American Type Culture Collection Lactobacillus strains. Most women were colonized by L. crispatus (32%), followed by L. jensenii (23%), a previously undescribed species designated L. 1086V (15%), L. gasseri (5%), L. fermentum (0.3%), L. oris (0.3%), L. reuteri (0.3%), L. ruminis (0.3%), and L. vaginalis (0.3%). H2O2 was produced by 95% of L. crispatus and 94% of L. jensenii isolates, compared with only 9% of L. 1086V. Colonization by L. crispatus or L. jensenii was positively associated with being white (P<.001), age >/=20 years (P=.05), barrier contraceptive usage (P=.008), and lower frequency of bacterial vaginosis (P<.001) and gonorrhea (P=.03). L. crispatus and L. jensenii, not L. acidophilus, are the most common species of vaginal lactobacilli.
据报道，嗜酸乳杆菌是阴道中的主要菌种。使用针对20株美国典型培养物保藏中心乳酸杆菌菌株的全染色体DNA探针，对从215名性活跃女性中分离出的阴道乳酸杆菌进行了鉴定。大多数女性的阴道中定殖的是卷曲乳杆菌（32%），其次是詹氏乳杆菌（23%）、一种先前未描述的名为1086V乳杆菌的菌种（15%）、加氏乳杆菌（5%）、发酵乳杆菌（0.3%）、口乳杆菌（0.3%）、罗伊氏乳杆菌（0.3%）、瘤胃乳杆菌（0.3%）和阴道乳杆菌（0.3%）。95%的卷曲乳杆菌分离株和94%的詹氏乳杆菌分离株可产生过氧化氢，相比之下，1086V乳杆菌只有9%能产生过氧化氢。卷曲乳杆菌或詹氏乳杆菌定殖与白人（P<0.001）、年龄≥20岁（P=0.05）、使用屏障避孕法（P=0.008）以及细菌性阴道病（P<0.001）和淋病（P=0.03）的低发病率呈正相关。阴道乳酸杆菌中最常见的菌种是卷曲乳杆菌和詹氏乳杆菌，而非嗜酸乳杆菌。
