Daniels T E, Silverman S, Michalski J P, Greenspan J S, Sylvester R A, Talal N
Oral Surg Oral Med Oral Pathol. 1975 Jun;39(6):875-85. doi: 10.1016/0030-4220(75)90108-5.
This study reports the results of an interdisciplinary approach to the diagnosis of Sjögren's syndrome in 100 patients. Ocular and systemic diagnoses and oral features from the history and physical examination are correlated with measurements of stimulated parotid flow rate and labial salivary gland histopathology. A new diagnostic criterion is introduced whereby labial salivary gland focus scores are used to establish the presence of the oral component of Sjögren's syndrome in place of the subjective evaluation of xerostomia. The differential diagnosis of the oral clinical features of Sjögren's syndrome and the clinical management of the oral component of this disease are discussed.
本研究报告了对100例干燥综合征患者进行跨学科诊断的结果。眼部和全身诊断以及病史和体格检查中的口腔特征与刺激腮腺流速测量和唇腺组织病理学检查结果相关。引入了一种新的诊断标准,即使用唇腺灶性评分来确定干燥综合征口腔病变的存在,以取代对口干的主观评估。文中还讨论了干燥综合征口腔临床特征的鉴别诊断以及该疾病口腔病变的临床处理。