Spahis J K, Wilson G N
Am J Med Genet. 1999 Jun 25;89(2):96-9.
Two hundred and sixteen infant evaluations were selected for analysis from those of 669 outpatients (930 total visits) at a weekly Down syndrome clinic. Each record contained perinatal history and physical examination results, and 191 of the 216 included a systematic interview regarding parental experiences with diagnosis and counseling. Gastrointestinal problems (77% of neonates), cardiac anomalies (38%), and hematologic problems (11%) were the most common complications; cited problems included anal stenosis (11%), which is described as a newly recognized cause of constipation in early infancy. Counseling experiences were positive in 66 (34%) of the 191 parent interviews, with counselor knowledge, timing, setting, and attitudes being cited as key factors. Appropriate counseling and surveillance for gastrointestinal problems can greatly facilitate parental adjustment to the neonate with Down syndrome.
从每周一次的唐氏综合征门诊669名门诊患者（共930次就诊）的评估中，选取了216例婴儿评估进行分析。每份记录都包含围产期病史和体格检查结果，216例中的191例包括了关于父母对诊断和咨询经历的系统访谈。胃肠道问题（77%的新生儿）、心脏异常（38%）和血液学问题（11%）是最常见的并发症；提及的问题包括肛门狭窄（11%），其被描述为婴儿早期便秘的一个新认识到的原因。在191例家长访谈中，66例（34%）的咨询经历是积极的，咨询者的知识、时机、环境和态度被认为是关键因素。对胃肠道问题进行适当的咨询和监测可以极大地促进父母对唐氏综合征新生儿的适应。
