Motohashi N
National Center Hospital for Mental, Nervous and Muscular Disorders, Kodarira, Tokyo, Japan.
Psychiatry Clin Neurosci. 1999 Oct;53 Suppl:S41-4.
The algorithms for the treatment of bipolar disorder are presented. Lithium is the first choice when treating acute mania. Other options are antipsychotics or mood stabilizers such as carbamazepine and valproate. Mood stabilizers (often in combinations) are drugs of choice for maintenance treatment. For the treatment of acute depression under lithium maintenance, increase doses of lithium or addition of antidepressants may be necessary.
本文介绍了双相情感障碍的治疗算法。锂盐是治疗急性躁狂发作的首选药物。其他选择包括抗精神病药物或心境稳定剂，如卡马西平和丙戊酸盐。心境稳定剂（通常联合使用）是维持治疗的首选药物。对于锂盐维持治疗期间的急性抑郁发作，可能需要增加锂盐剂量或加用抗抑郁药物。
