Soulat J M, Lauque D, Esquirol Y, Déprés M, Giron J, Claudel R, Carles P
Department of Occupational Médecine, Pavillon Turiaf, Centre Hospitalier-Universitaire Purpan, 31059 Toulouse, France.
Am J Ind Med. 1999 Dec;36(6):593-601. doi: 10.1002/(sici)1097-0274(199912)36:6<593::aid-ajim1>3.0.co;2-z.
characterize To the effects of high asbestos exposure during annual periods of insulation.
170 ex-workers underwent clinical examination, spirometry, standard chest X-rays and high-resolution computed tomography (HRCT). Asbestos exposure was retrospectively assessed for latency, duration, and intensity.
Sixty-six percent of these workers were annually exposed to high concentrations of asbestos dust. Respiratory symptoms were mild. One hundred and nineteen subjects had pleural or pulmonary changes on HRCT, compatible with asbestos exposure. Localized pleural thickening was found in 113 subjects (66.5%); pulmonary nodules or lines in 35 (20.6%). The presence of pleural plaques was linked to intensity of asbestos exposure (P <.01), and length of employment (P <.05). Parenchymal lesions were related to intensity (P <.05) and duration of exposure (P <.05). Lung function of subjects with X-ray changes was not significantly altered.
Annual asbestos exposure led to a high prevalence of pleural plaques and to mild parenchymal anomalies.
描述年度绝缘期间高石棉暴露的影响。
170名前工人接受了临床检查、肺功能测定、标准胸部X线检查和高分辨率计算机断层扫描(HRCT)。回顾性评估石棉暴露的潜伏期、持续时间和强度。
这些工人中有66%每年接触高浓度石棉粉尘。呼吸道症状较轻。119名受试者的HRCT显示胸膜或肺部有改变,与石棉暴露相符。113名受试者(66.5%)发现局限性胸膜增厚;35名(20.6%)有肺结节或条索状影。胸膜斑的存在与石棉暴露强度(P<.01)和工作年限(P<.05)有关。实质性病变与暴露强度(P<.05)和暴露持续时间(P<.05)有关。X线有改变的受试者肺功能无明显改变。
年度石棉暴露导致胸膜斑的高患病率和轻度实质性异常。