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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Callister R J, Schofield P R, Sah P

Neuroscience Group, School of Biomedical Sciences, Faculty of Medicine and Health Sciences, University of Newcastle, Callaghan, Australia.

Clin Exp Pharmacol Physiol. 1999 Nov;26(11):929-31. doi: 10.1046/j.1440-1681.1999.03148.x.

The accompanying articles in this symposium describe several different approaches used to examine the function of glycine and GABA receptors, including pharmacology and neurochemistry, permeability and agonist-binding approaches, the use of mutated recombinant receptors and monoclonal antibody staining to examine receptor distribution on neurons. 2. The present review focuses on the use of another, quite different, approach: the use of murine mutants, spasmodic and spastic, to study the function of native glycine receptors at synaptic connections within the central nervous system.

本次研讨会的相关文章描述了几种用于研究甘氨酸和γ-氨基丁酸（GABA）受体功能的不同方法，包括药理学和神经化学、通透性和激动剂结合方法、使用突变重组受体以及单克隆抗体染色来检测受体在神经元上的分布。2. 本综述重点关注另一种截然不同的方法：利用痉挛型和强直型小鼠突变体来研究中枢神经系统内突触连接处天然甘氨酸受体的功能。

Callister R J, Schofield P R, Sah P

Neuroscience Group, School of Biomedical Sciences, Faculty of Medicine and Health Sciences, University of Newcastle, Callaghan, Australia.

Clin Exp Pharmacol Physiol. 1999 Nov;26(11):929-31. doi: 10.1046/j.1440-1681.1999.03148.x.

The accompanying articles in this symposium describe several different approaches used to examine the function of glycine and GABA receptors, including pharmacology and neurochemistry, permeability and agonist-binding approaches, the use of mutated recombinant receptors and monoclonal antibody staining to examine receptor distribution on neurons. 2. The present review focuses on the use of another, quite different, approach: the use of murine mutants, spasmodic and spastic, to study the function of native glycine receptors at synaptic connections within the central nervous system.

本次研讨会的相关文章描述了几种用于研究甘氨酸和γ-氨基丁酸（GABA）受体功能的不同方法，包括药理学和神经化学、通透性和激动剂结合方法、使用突变重组受体以及单克隆抗体染色来检测受体在神经元上的分布。2. 本综述重点关注另一种截然不同的方法：利用痉挛型和强直型小鼠突变体来研究中枢神经系统内突触连接处天然甘氨酸受体的功能。