Tsai T C, Hou C C, Chou M S, Chen W H, Liu J S
Department of Diagnostic Radiology, Chi-Mei Foundation Hospital, Tainan, Taiwan, Republic of China.
Kaohsiung J Med Sci. 1999 Sep;15(9):556-61.
The authors describe a case of rhinosino-orbital mucormycosis with cavernous sinus thrombosis in association with internal carotid artery occlusion diagnosed by use of computerized tomography (CT) and magnetic resonance imaging (MRI). Cranial CT is a useful imaging tool in the diagnosis of rhinosinal invasive fungal disease and MRI offers excellent aid in the detection of intracranial extension. Early diagnosis and rapid institution of surgical debridement and antifungal therapy is the rule of thumb in treating this disorder. In our patient, surgically inaccessible bone lesion and involvement of the central nervous system are taken as major causes for his grave outcome. In addition, failure to advance appropriate amphotericin B dosage may also make the infectious process uncontrollable in this patient.
作者描述了一例经计算机断层扫描（CT）和磁共振成像（MRI）诊断为伴有海绵窦血栓形成及颈内动脉闭塞的鼻-鼻窦-眼眶毛霉菌病病例。头颅CT是诊断鼻窦侵袭性真菌病的有用影像学工具，而MRI在检测颅内扩展方面提供了极佳的帮助。早期诊断并迅速进行手术清创和抗真菌治疗是治疗这种疾病的基本原则。在我们的患者中，手术难以触及的骨病变和中枢神经系统受累被视为其严重后果的主要原因。此外，未能增加适当剂量的两性霉素B也可能使该患者的感染过程无法得到控制。
