De Bandt J P, Cynober L A
Laboratoire de Biochimie A, Hôpital Necker-Enfants Malades, Faculté de Pharmacie, Université Paris V, France.
Curr Opin Clin Nutr Metab Care. 1998 May;1(3):263-72. doi: 10.1097/00075197-199805000-00005.
Experimental studies have clearly demonstrated both the indispensability in stress situations of amino acids, previously considered to be non-essential, and the importance of the specific properties of these same amino acids. Glutamine, arginine and their precursors/metabolites, ornithine and alpha-ketoglutarate, exert anabolic or anticatabolic effects through their involvement in protein metabolism, in the immune response and in cell proliferation. Clinical studies suggest that the supplementation of nutritional therapy with these amino acids can be of significant benefit for injured patients.
