蛋白质热量营养不良时的血浆生长调节素活性
Plasma somatomedin activity in protein calorie malnutrition.
作者信息
Mohan P S, Jaya Rao K S
出版信息
Arch Dis Child. 1979 Jan;54(1):62-4. doi: 10.1136/adc.54.1.62.
Abstract
Somatomedin activity was assayed in the plasma of children suffering from protein calorie malnutrition by a bioassay using rat cartilage and expressed as sulphate uptake ratio. The sulphate uptake ratio was particularly reduced in kwashiorkor. In marasmus there was a slight reduction and the levels were still in the normal range. Plasma growth hormone (GH) levels were raised in kwashiorkor but were in the normal range in marasmus. Reduction in sulphate uptake ratio was observed only when plasma albumin levels were less than 2.5 g/100 ml (25 g/l). A rise in plasma GH was also observed but only below this threshold level.
摘要
采用大鼠软骨生物测定法，对患有蛋白质 - 热量营养不良的儿童血浆中的生长调节素活性进行了测定，并以硫酸盐摄取率表示。夸希奥科病（恶性营养不良）患儿的硫酸盐摄取率显著降低。消瘦症患儿的硫酸盐摄取率略有降低，但仍在正常范围内。夸希奥科病患儿的血浆生长激素（GH）水平升高，但消瘦症患儿的血浆生长激素水平在正常范围内。仅当血浆白蛋白水平低于2.5 g/100 ml（25 g/l）时，才观察到硫酸盐摄取率降低。同时也观察到血浆GH升高，但仅在该阈值水平以下。
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本文引用的文献
1
Studies on growth hormone secretion in protein-calorie malnutrition.蛋白质-热量营养不良时生长激素分泌的研究。
Am J Clin Nutr. 1968 May;21(5):482-7. doi: 10.1093/ajcn/21.5.482.
2
Growth hormone in infant malnutrition: the arginine test in marasmus and kwashiorkor.
Br J Nutr. 1971 Sep;26(2):169-75. doi: 10.1079/bjn19710023.
3
The production of sulphation factor' by rat liver.
J Endocrinol. 1972 Jan;52(1):1-9. doi: 10.1677/joe.0.0520001.
4
Sulfation factor regulation of skeletal growth. A stable mechanism dependent on intermittent growth hormone secretion.
Am J Med. 1971 Mar;50(3):277-80. doi: 10.1016/0002-9343(71)90214-2.
5
A simplified technique for the determination of growth hormone dependent sulfation factor, using intact animals.一种使用完整动物测定生长激素依赖性硫酸化因子的简化技术。
Acta Endocrinol (Copenh). 1968 Apr;57(4):557-64. doi: 10.1530/acta.0.0570557.
6
Progressive changes in serum cortisol, insulin and growth hormone concentrations and their relationship to the distorted amino acid pattern during the development of kwashiorkor.夸希奥科病发展过程中血清皮质醇、胰岛素和生长激素浓度的渐进性变化及其与氨基酸模式紊乱的关系。
Br J Nutr. 1973 May;29(3):399-422. doi: 10.1079/bjn19730117.
7
A simplified assay for somatomedin.一种生长调节素的简易检测方法。
J Endocrinol. 1972 Aug;54(2):365-6. doi: 10.1677/joe.0.0540365.
8
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J Pediatr. 1973 Jan;82(1):133-42. doi: 10.1016/s0022-3476(73)80031-9.
9
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J Clin Endocrinol Metab. 1972 Dec;35(6):863-7. doi: 10.1210/jcem-35-6-863.
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