Runciman S I, Baudinette R V, Gannon B J, Lipsett J
Department of Anatomy and Histology, School of Medicine, The Flinders University of South Australia, Adelaide, Australia.
Respir Physiol. 1999 Oct 15;118(1):61-75. doi: 10.1016/s0034-5687(99)00068-7.
Postnatal lung development in the tammar wallaby was investigated using transmission electron microscopy and stereological morphometry. Volume densities of interstitial, epithelial and endothelial tissue and capillaries in the parenchymal septa were measured as were surface densities of the airspaces and gas exchange capillaries. Absolute changes in these parameters were related to body mass. Three phases of development were identified. During the ectothermic period, in the first 70 days after birth when the lung was in the terminal air sac phase, the most marked change was an increase in volume density of septal interstitium. The transitional period between ectothermy and endothermy, between 70 and 180 days after birth, corresponded to the alveolar phase and was characterised by accelerated increase in air space surface area. Maturation of the parenchymal septa and establishment of the mature capillary system occurred largely after 180 days when endothermy was established. The anatomical diffusion factor in the tammar wallaby adult is similar to that for eutherians.
利用透射电子显微镜和体视形态测量法对帚尾袋貂出生后的肺发育进行了研究。测量了实质间隔中间质、上皮和内皮组织及毛细血管的体积密度，以及气腔和气体交换毛细血管的表面密度。这些参数的绝对变化与体重相关。确定了三个发育阶段。在变温期，即出生后的前70天，肺部处于终末气囊阶段，最显著的变化是间隔间质体积密度增加。变温与恒温之间的过渡期，即出生后70至180天，对应肺泡阶段，其特征是气腔表面积加速增加。实质间隔的成熟和成熟毛细血管系统的建立主要发生在180天后恒温建立时。成年帚尾袋貂的解剖扩散因子与真兽类相似。
