Muntz F H
IDEXX CVDL, Mount Waverly, Vic, Australia.
Vet Pathol. 1999 Nov;36(6):631-2. doi: 10.1354/vp.36-6-631.
An aging lactating alpaca was presented in sternal recumbency. Although bright and alert, she did not respond to symptomatic treatment and was euthanized 5 weeks after initial presentation. Gross postmortem examination revealed purulent material in the pulmonary airways. Histologic examination of the lungs revealed an extensive pyogranulomatous pneumonia with bronchiectasis. There were abundant fungal hyphae and high numbers of associated oxalate crystals, which were presumed to have been produced by the fungus. Low numbers of yeast cells were also present. Microbiological culture of tissues on horse blood agar and Sabouraud's agar identified the fungus to be Aspergillus niger. There was also moderate growth of Candida albicans. Calcium oxalate crystals in cytologic and histologic preparations can suggest an underlying Aspergillus infection. This is the first reported veterinary case of pneumonia due to Aspergillus niger infection and the associated production of oxalate crystals.
一只老龄泌乳羊驼呈仰卧位被送来就诊。尽管精神尚可且警觉，但它对对症治疗无反应，在初次就诊5周后实施了安乐死。尸体剖检肉眼可见肺气道内有脓性物质。肺部组织学检查显示为广泛的化脓性肉芽肿性肺炎伴支气管扩张。有大量真菌菌丝以及大量相关的草酸钙晶体，推测这些晶体由真菌产生。也存在少量酵母细胞。在马血琼脂和沙氏琼脂上对组织进行微生物培养，鉴定该真菌为黑曲霉。同时还有白色念珠菌的中度生长。细胞学和组织学制剂中的草酸钙晶体可能提示潜在的曲霉感染。这是首例报道的由黑曲霉感染及相关草酸钙晶体产生导致的兽医肺炎病例。
