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猪模型中腹腔镜与腹腔镜辅助供肾切除术的比较

Laparoscopic v laparoscopy-assisted donor nephrectomy in the porcine model.

作者信息

West D A, Rallo M C, Moore R G, Vogler G A, Niehoff M, Parra R O, Varma C, Smith G S

机构信息

Division of Urology, St. Louis University Health Sciences Center, Missouri, USA.

出版信息

J Endourol. 1999 Sep;13(7):513-5. doi: 10.1089/end.1999.13.513.

DOI:10.1089/end.1999.13.513
PMID:10569526
Abstract

PURPOSE

Laparoscopic donor nephrectomy is an established procedure in the porcine model. We sought to compare intraoperative variables between live laparoscopic (LAP) and laparoscopy-assisted (LAP-A) donor nephrectomy.

MATERIALS AND METHODS

Eight domestic pigs underwent either traditional laparoscopic donor nephrectomy (N = 4) or laparoscopy-assisted donor nephrectomy (N = 4) using the Pneumosleeve followed by conventional heterotopic autotransplantation.

RESULTS

No significant differences were noted between the groups with regard to vessel length, ureteral length, or postoperative urine output. The operating room time was 108+/-12 minutes in the LAP group v 75.8+/-10.3 minutes in the LAP-A group (P = 0.0065). Although the difference was not statistically significant, warm ischemic time, tended to be lower in the LAP-A than the LAP group: 70+/-3.0 seconds v 135+/-57 seconds, respectively (P = 0.059). Graft survival was identical in the two groups.

CONCLUSION

Laparoscopy-assisted (via Pneumosleeve) live donor nephrectomy shortens the operative time without affecting graft survival in the domestic swine model.

摘要

目的

腹腔镜供肾切除术在猪模型中是一种成熟的手术方法。我们试图比较活体腹腔镜(LAP)和腹腔镜辅助(LAP-A)供肾切除术的术中变量。

材料与方法

八只家猪接受了传统腹腔镜供肾切除术(N = 4)或使用气袖式腹腔镜辅助供肾切除术(N = 4),随后进行传统的异位自体移植。

结果

两组在血管长度、输尿管长度或术后尿量方面无显著差异。LAP组的手术室时间为108±12分钟,而LAP-A组为75.8±10.3分钟(P = 0.0065)。虽然差异无统计学意义,但LAP-A组的热缺血时间倾向于低于LAP组:分别为70±3.0秒和135±57秒(P = 0.059)。两组的移植物存活率相同。

结论

在家猪模型中,腹腔镜辅助(通过气袖式)活体供肾切除术可缩短手术时间,且不影响移植物存活率。

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