Phadke K P, Kwan Y L, Young S G
Aust N Z J Med. 1978 Oct;8(5):539-43. doi: 10.1111/j.1445-5994.1978.tb02596.x.
Two patients with IgA myeloma and one patient with kappa light chain disease developed sideroblastic anaemia from two to four years after the initial diagnosis. All had previously received radiotherapy and chemotherapy (melphalan and prednisone). In two patients the myeloma was quiescent when the sideroblastic change occurred. Leukaemia occurred in two patients two and seven months respectively after the diagnosis of sideroblastic anaemia was made. In one of them, the myeloma became active again at the same time. The development of sideroblastic anaemia may be a pre-leukaemic event and may be recognised by the appearance of a dimorphic blood film.
两名IgA骨髓瘤患者和一名κ轻链病患者在初次诊断后两到四年出现铁粒幼细胞性贫血。所有患者此前均接受过放疗和化疗（美法仑和泼尼松）。两名患者出现铁粒幼细胞改变时骨髓瘤处于静止状态。两名患者在诊断为铁粒幼细胞性贫血后分别于两个月和七个月发生白血病。其中一名患者的骨髓瘤同时再次活跃。铁粒幼细胞性贫血的发生可能是白血病前期事件，可通过双形血片的出现来识别。
