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难治性铁粒幼细胞贫血先于“无分泌型”浆细胞骨髓瘤(作者译)

["Non-secreting" plasma cell myeloma preceded by refractory sideroblastic anemia (author's transl)].

作者信息

Moreau L, Cosson A, Valcke J C, Preud'homme J L, Philbert M, Favriel J M

出版信息

Sem Hop. 1979;55(39-40):1794-6.

PMID:232775
Abstract

The authors report the association of a refractory sideroblastic anemia and a "non-excreting" plasma cell myeloma. The anemia was observed 8 years before the onset of the myeloma, which had typical hematological characteristics. Both kappa and gamma light chains were found in the cytoplasm and on the surface of the plasma cells. Pathologic characteristics of this type of myeloma are briefly recalled, as well as the relationships between sideroblastic anemia and kahler's disease, an example of disorders of two lines of hematopoiesis (erythrocytes and leucocytes).

摘要

作者报告了难治性铁粒幼细胞贫血与“无分泌型”浆细胞骨髓瘤之间的关联。该贫血在骨髓瘤发病前8年被观察到,骨髓瘤具有典型的血液学特征。在浆细胞的细胞质和表面均发现了κ和γ轻链。本文简要回顾了这类骨髓瘤的病理特征,以及铁粒幼细胞贫血与卡勒病(造血两系即红细胞和白细胞的疾病的一个例子)之间的关系。

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