Letzelter N, Rouberol F, Vasselon J, Hullo A
Service d'ophtalmologie, Centre Hospitalier Lyon Sud, Pierre-Benite.
J Fr Ophtalmol. 1999 Oct;22(8):881-3.
We report the case of a primitive ocular lymphoma occurring in a 48 year old patient. Non-Hodgkin's lymphomas are usually found in ocular localizations, and are often associated with a lymphomatous cerebral affection. The most frequent mode of presentation of these rare intra ocular tumors is usually posterior uveitis with chorioretinal lesions, and must be suspected for every long-standing chronic uveitis, especially posterior ones. The diagnosis can only be based on histological or cytological analysis. Our patient presented a primary ocular lymphoma which was initially revealed by an anterior uveitis and had evolved into a panuveitis that was resistant to treatment. The initial checkup of this uveitis remained negative and did not allow for an etiological diagnosis. The eye came less operational, hypertonic crisis became more frequent and controlled less and less by the treatment, therefore the patient had to be enucleated in order to establish a diagnosis and for therapeutic reasons. The histology revealed the existence of a NK lymphoma.
我们报告了一例发生在一名48岁患者身上的原发性眼内淋巴瘤病例。非霍奇金淋巴瘤通常见于眼部，且常与淋巴瘤性脑病变相关。这些罕见的眼内肿瘤最常见的表现形式通常是伴有脉络膜视网膜病变的后葡萄膜炎，对于每一例长期存在的慢性葡萄膜炎，尤其是后葡萄膜炎，都必须怀疑有这种情况。诊断只能基于组织学或细胞学分析。我们的患者表现为原发性眼内淋巴瘤，最初表现为前葡萄膜炎，随后发展为对治疗有抵抗性的全葡萄膜炎。此次葡萄膜炎的初始检查结果为阴性，无法做出病因诊断。眼睛的手术适应性降低，高眼压危机变得更加频繁，治疗对其控制越来越差，因此为了明确诊断和治疗原因，不得不对患者进行眼球摘除术。组织学检查显示存在自然杀伤细胞淋巴瘤。
