• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[结膜肿瘤的鉴别诊断与治疗选择]

[Differential diagnosis and treatment options for conjunctival tumors].

作者信息

Holbach L M, Pogorelov P, Kruse F E

机构信息

Augenklinik mit Poliklinik der Universität Erlangen-Nürnberg, Schwabachanlage 6, 91054, Erlangen.

出版信息

Ophthalmologe. 2007 Jun;104(6):521-38; quiz 538. doi: 10.1007/s00347-007-1551-8.

DOI:10.1007/s00347-007-1551-8
PMID:17530261
Abstract

The diagnostic classification of most conjunctival tumors is based on case history, inspection, and examination with the slit lamp microscope. Further imaging procedures are rarely indicated when malignant processes are not circumscribed. Clinical classification then also includes palpation and echographic examination of regional lymph nodes. Pigmented and nonpigmented melanocytic nevi are the most frequent conjunctival tumors. An important practical biomicroscopic cardinal symptom of the most frequent nevi is the presence of epithelial pseudocysts. Essential in practice is the histopathological confirmation of the clinical diagnosis, e.g., distinguishing between nonpigmented melanomas and sebaceous gland carcinomas with a pagetoid growth pattern or squamous cell carcinomas. Depending on the course and findings, the following therapeutic measures can be indicated: cryotherapy, chemotherapy, radiotherapy, modified enucleation, orbital exenteration, or a combination of different methods.

摘要

大多数结膜肿瘤的诊断分类基于病史、检查以及裂隙灯显微镜检查。当恶性病变范围不局限时,很少需要进一步的影像学检查。临床分类还包括对区域淋巴结的触诊和超声检查。色素性和非色素性黑素细胞痣是最常见的结膜肿瘤。最常见痣的一个重要的实际生物显微镜主要症状是上皮性假性囊肿的存在。在实践中,临床诊断的组织病理学确认至关重要,例如区分非色素性黑色素瘤与具有派杰样生长模式的皮脂腺癌或鳞状细胞癌。根据病程和检查结果,可采取以下治疗措施:冷冻疗法、化疗、放疗、改良眼球摘除术、眼眶内容剜除术或不同方法的联合应用。

相似文献

1
[Differential diagnosis and treatment options for conjunctival tumors].[结膜肿瘤的鉴别诊断与治疗选择]
Ophthalmologe. 2007 Jun;104(6):521-38; quiz 538. doi: 10.1007/s00347-007-1551-8.
2
[Focus on clinical and pathological management of conjunctival melanocytic tumors].[聚焦结膜黑素细胞肿瘤的临床与病理管理]
Ann Pathol. 2018 Jun;38(3):153-163. doi: 10.1016/j.annpat.2018.03.006. Epub 2018 May 24.
3
[Prognosis of primary malignant tumors of the conjunctiva].[结膜原发性恶性肿瘤的预后]
J Fr Ophtalmol. 2015 Jun;38(6):477-85. doi: 10.1016/j.jfo.2014.10.017. Epub 2015 May 11.
4
[Spontaneous changes in pigmentation in a conjunctival nevus].[结膜痣色素沉着的自发变化]
Klin Monbl Augenheilkd. 1984 Jan;184(1):46-7. doi: 10.1055/s-2008-1054408.
5
Current appraisal of conjunctival melanocytic tumors: classification and treatment.当前对结膜黑色素细胞肿瘤的评估:分类与治疗。
Future Oncol. 2011 Mar;7(3):435-46. doi: 10.2217/fon.11.12.
6
[777 cases of the primary conjunctival neoplasms].777例原发性结膜肿瘤
Yan Ke Xue Bao. 1995 Dec;11(4):211-5.
7
[Malignant conjunctival melanoma. Clinical review with recommendations for diagnosis, therapy and follow-up].[恶性结膜黑色素瘤。关于诊断、治疗及随访建议的临床综述]
Klin Monbl Augenheilkd. 2002 Oct;219(10):710-21. doi: 10.1055/s-2002-35693.
8
Inflammatory juvenile compound nevi: A melanoma is not all that it appears to be.炎症性幼年复合痣:黑色素瘤并非如其表面所见那么简单。
Arch Soc Esp Oftalmol (Engl Ed). 2019 Feb;94(2):90-94. doi: 10.1016/j.oftal.2018.06.022. Epub 2018 Aug 8.
9
[Malignant melanoma of the conjunctiva].[结膜恶性黑色素瘤]
Arq Bras Oftalmol. 2012 Jul-Aug;75(4):289-95. doi: 10.1590/s0004-27492012000400016.
10
[Melanotic eyelid and conjunctival tumors].[黑色素性眼睑及结膜肿瘤]
Med Klin. 1981 Aug 28;76(18):495-7.

引用本文的文献

1
[Evaluation of the accuracy of clinical diagnosis of conjunctival neoplasms : Comparison with histological findings after excision].[结膜肿瘤临床诊断准确性的评估:与切除术后组织学检查结果的比较]
Ophthalmologie. 2024 May;121(5):391-396. doi: 10.1007/s00347-024-02009-5. Epub 2024 Mar 6.
2
[Pathology and prognostic factors of conjunctival melanoma].[结膜黑色素瘤的病理学及预后因素]
Ophthalmologe. 2015 Nov;112(11):892, 894-8. doi: 10.1007/s00347-015-0148-x.

本文引用的文献

1
Different genetic pathways in the development of periocular sebaceous gland carcinomas in presumptive Muir-Torre syndrome patients.疑似穆尔-托雷综合征患者眼周皮脂腺癌发生过程中的不同遗传途径。
Hum Mutat. 2006 Feb;27(2):155-62. doi: 10.1002/humu.20281.
2
[Adjuvant topical interferon-alpha-2b treatment in epithelial tumors of the ocular surface].[眼表上皮肿瘤的辅助性局部应用干扰素-α-2b治疗]
Ophthalmologe. 2006 Feb;103(2):124-8. doi: 10.1007/s00347-005-1249-8.
3
Frequency and clinical features of visceral malignancy in a consecutive case series of patients with periocular sebaceous gland carcinoma.
一组连续性眼周皮脂腺癌患者内脏恶性肿瘤的发生率及临床特征
Graefes Arch Clin Exp Ophthalmol. 2004 Aug;242(8):674-8. doi: 10.1007/s00417-003-0856-9. Epub 2004 Jun 29.
4
[Association of malignant tumors of the conjunctiva and HIV infection in Kinshasa (D. R. Congo). First results].[金沙萨(刚果民主共和国)结膜恶性肿瘤与HIV感染的关联。初步结果]
Ophthalmologe. 2004 Oct;101(10):1011-6. doi: 10.1007/s00347-003-0960-6.
5
Benign fibrous histiocytoma of the corneoscleral limbus: unique clinicopathologic features.
Arch Ophthalmol. 2003 Dec;121(12):1776-9. doi: 10.1001/archopht.121.12.1776.
6
[Management of conjunctival malignant melanoma associated with primary acquired melanosis (PAM) using 0.02% mitomycin C eyedrops].[使用0.02%丝裂霉素C滴眼液治疗与原发性获得性黑素沉着症(PAM)相关的结膜恶性黑色素瘤]
Ophthalmologe. 2003 Sep;100(9):708-12. doi: 10.1007/s00347-002-0765-z.
7
Ocular adnexal lymphomas: five case presentations and a review of the literature.眼附属器淋巴瘤:5例病例报告及文献综述
Surv Ophthalmol. 2002 Sep-Oct;47(5):470-90. doi: 10.1016/s0039-6257(02)00337-5.
8
[Orbital exenteration in therapy-resistant painful scleritis-associated inflammation of orbital soft tissues].[眶内容剜除术治疗难治性疼痛性巩膜炎相关眼眶软组织炎症]
Klin Monbl Augenheilkd. 2002 Jun;219(6):462-4. doi: 10.1055/s-2002-32882.
9
[Differential eyelid tumors diagnosis. II].
Ophthalmologe. 2002 Jun;99(6):490-507; quiz 508-9. doi: 10.1007/s00347-002-0636-7.
10
Loss of fragile histidine triad (FHIT) expression and microsatellite instability in periocular sebaceous gland carcinoma in patients with Muir-Torre syndrome.穆尔-托雷综合征患者眼周皮脂腺癌中脆性组氨酸三联体(FHIT)表达缺失与微卫星不稳定性
Am J Ophthalmol. 2002 Jul;134(1):147-8. doi: 10.1016/s0002-9394(02)01434-4.