Guerra-Tapia A, Isarría María José
Dermatology Department, 12 de Octubre Hospital, Madrid, Spain.
Pediatr Dermatol. 2005 Sep-Oct;22(5):427-9. doi: 10.1111/j.1525-1470.2005.00108.x.
Leukoderma in association with congenital melanocytic nevi is a rare phenomenon; nevertheless several reports have been published in the literature. We present a 15-year-old boy born with a pigmented lesion on the lower and upper eyelid diagnosed as a congenital divided nevus of the eyelid. At the age of 13, he developed a depigmented area around the nevus and was diagnosed at first as having a halo nevus in a congenital nevus. Over the next two years, an area of depigmentation appeared around the contralateral eye. At the present time, the patient has bilateral periocular depigmentation. Congenital divided nevus of the eyelid is a rare lesion, and no reports have been published to date of depigmentation in association with this lesion. Our patient presented with depigmentation around the nevus as in a halo nevus phenomenon, although at the present time, the depigmented area has a symmetric periocular distribution, and therefore can be labeled as periocular vitiligo associated with a congenital divided nevus.
白癜风合并先天性黑素细胞痣是一种罕见现象；尽管如此，文献中已有多篇报道。我们报告一名15岁男孩，出生时上下眼睑有色素沉着病变，诊断为先天性眼睑分裂痣。13岁时，他在痣周围出现了色素脱失区域，最初被诊断为先天性痣中的晕痣。在接下来的两年里，对侧眼周围出现了色素脱失区域。目前，该患者双侧眼周色素脱失。先天性眼睑分裂痣是一种罕见病变，迄今为止尚无与此病变相关的色素脱失报道。我们的患者痣周围出现色素脱失，如同晕痣现象，尽管目前色素脱失区域呈对称性眼周分布，因此可被标记为与先天性眼睑分裂痣相关的眼周白癜风。
