Hasselbacher P
Arthritis Rheum. 1979 Mar;22(3):243-50. doi: 10.1002/art.1780220306.
Synovial fluid C3 was measured by electroimmunoassay. When C3 was expressed as mg/ml, the amounts found in Reiter's disease, psoriatic arthritis, gout, and systemic lupus erythematosus were significantly different from degenerative arthritis. When C3 was corrected for total protein, the levels for rheumatoid arthritis, Reiter's disease, psoriatic arthritis, and systemic lupus were significantly different from degenerative arthritis. When C3 was corrected for synovial fluid globulin, only rheumatoid arthritis and systemic lupus were significantly different from degenerative arthritis. Correction of C3 for globulin increases the difference between rheumatoid arthritis and degenerative arthritis. A proportion of gouty fluids with a relative decrease in C3 is demonstrated. It is argued that correction of C3 for globulin is more meaningful than correction for total protein. While many nonrheumatoid inflammatory effusions demonstrate split products of C3, the majority of fluids from patients with systemic lupus have none.
通过电免疫测定法测量滑液中的C3。当C3以mg/ml表示时，赖特综合征、银屑病关节炎、痛风和系统性红斑狼疮中发现的C3量与退行性关节炎有显著差异。当C3针对总蛋白进行校正时，类风湿关节炎、赖特综合征、银屑病关节炎和系统性红斑狼疮的水平与退行性关节炎有显著差异。当C3针对滑液球蛋白进行校正时，只有类风湿关节炎和系统性红斑狼疮与退行性关节炎有显著差异。对球蛋白校正C3会增加类风湿关节炎和退行性关节炎之间的差异。有一部分痛风性滑液显示C3相对减少。有人认为，对球蛋白校正C3比针对总蛋白校正更有意义。虽然许多非类风湿性炎性渗出液显示有C3的裂解产物，但大多数系统性红斑狼疮患者的滑液中没有。
