Margo C E
Department of Ophthalmology, Watson Clinic, LLP, Lakeland, Florida 33805, USA.
Am J Ophthalmol. 1999 Nov;128(5):635-6. doi: 10.1016/s0002-9394(99)00302-5.
To determine the accuracy, specificity, and sensitivity of the clinical diagnosis of malignant tumor of the eyelid.
Analysis of consecutively submitted biopsy specimens of the eyelid for 1 year to a regional ophthalmic pathology laboratory.
Agreement was noted between clinical and histopathologic diagnoses on 72 (84%) of 86 eyelid biopsy specimens received over 12 months. Ten (11.6%) clinical diagnoses of suspected malignant eyelid tumor showed benign skin conditions, and four (4.6%) clinical diagnoses of presumed benign conditions proved to be malignant.
The clinical assessment of eyelid malignancy by ophthalmologists is reasonably good when evaluated in terms of sensitivity (87.5%) and specificity (81.5%) of diagnosis. Lesions giving rise to the false-negative diagnosis of malignancy tend to be nodules with unremarkable surface features.
确定眼睑恶性肿瘤临床诊断的准确性、特异性和敏感性。
对一家地区眼科病理实验室连续1年提交的眼睑活检标本进行分析。
在12个月内收到的86份眼睑活检标本中,72份(84%)的临床诊断与组织病理学诊断相符。10份(11.6%)临床诊断为疑似眼睑恶性肿瘤的病例显示为良性皮肤疾病,4份(4.6%)临床诊断为假定良性疾病的病例被证实为恶性。
从诊断的敏感性(87.5%)和特异性(81.5%)来看,眼科医生对眼睑恶性肿瘤的临床评估相当不错。导致恶性肿瘤假阴性诊断的病变往往是表面特征不明显的结节。