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三级医疗中心眼睑肿瘤的临床病理特征:一项观察性前瞻性研究。

Clinicopathological profile of eyelid tumors at a tertiary care center: An observational prospective study.

作者信息

Prasad Nishi, Dubey Aditi, Patangia Priyanka, Kubrey Suraj S, Kumar Kavita

机构信息

Department of Ophthalmology, Gandhi Medical College, Bhopal, Madhya Pradesh, India.

Department of Pathology, Gandhi Medical College, Bhopal, Madhya Pradesh, India.

出版信息

Indian J Ophthalmol. 2025 Jun 1;73(Suppl 3):S399-S404. doi: 10.4103/IJO.IJO_905_24. Epub 2025 Apr 17.

Abstract

PURPOSE

The objective of this study was to study the clinical and histological profiles of eyelid tumors.

METHODS

This is an observational prospective study. A total 78 cases of eyelid tumors for a period of 1 year were included in this study. History was taken and clinical examination and radiological investigations were done as indicated, and all the cases were then subjected to surgical excision/incisional biopsy as per the size and clinical diagnosis. Histopathological examination of eyelid lesions was done, and the eyelid was primarily reconstructed. The data were compiled, and the statistical software SPSS version 20 was used for analysis.

RESULTS

A total of 78 cases of eyelid mass were included in this study within the study period. The mean age of the patients was 38.9 years. Out of 78 cases, 52.5% were male, while 47.5% were female. The male: female ratio was 1.05:1. The right-sided lesion was 54%. Benign cases were 66.6%, malignant cases were 18%, and inflammatory cases were 15.4%. Adnexal lesions are mostly benign, while epidermal lesions in elderly are malignant. Histologically, the most common benign lesion was epidermoid cyst and the most common malignant lesion was sebaceous cell carcinoma.

CONCLUSION

There is a vast variety of lid tumors based on tissue origin. Histological examination is essential to ascertain the origin and nature of growth of the eyelid tumors. Epidermal cysts were the most common benign lesions, and sebaceous carcinoma was the most common malignant tumor.

摘要

目的

本研究的目的是探讨眼睑肿瘤的临床和组织学特征。

方法

这是一项观察性前瞻性研究。本研究纳入了为期1年的78例眼睑肿瘤病例。记录病史,并根据需要进行临床检查和放射学检查,然后根据肿瘤大小和临床诊断对所有病例进行手术切除/切开活检。对眼睑病变进行组织病理学检查,并对眼睑进行一期重建。收集数据,使用统计软件SPSS 20版进行分析。

结果

在研究期间,本研究共纳入78例眼睑肿物病例。患者的平均年龄为38.9岁。78例中,男性占52.5%,女性占47.5%。男女比例为1.05:1。右侧病变占比54%。良性病例占66.6%,恶性病例占18%,炎症性病例占15.4%。附属器病变大多为良性,而老年人的表皮病变多为恶性。组织学上,最常见的良性病变是表皮样囊肿,最常见的恶性病变是皮脂腺癌。

结论

基于组织起源,眼睑肿瘤种类繁多。组织学检查对于确定眼睑肿瘤的起源和生长性质至关重要。表皮样囊肿是最常见的良性病变,皮脂腺癌是最常见的恶性肿瘤。

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