丝裂霉素C治疗复发性结膜乳头瘤病
Treatment of recurrent conjunctival papillomatosis with mitomycin C.
作者信息
Hawkins A S, Yu J, Hamming N A, Rubenstein J B
机构信息
Department of Ophthalmology, Rush Medical College of Rush University, Chicago, Illinois 60612, USA.
出版信息
Am J Ophthalmol. 1999 Nov;128(5):638-40. doi: 10.1016/s0002-9394(99)00221-4.
PURPOSE
To report an effective treatment for recurrent squamous papillomas of the conjunctiva with excision and application of mitomycin C.
METHOD
Case report.
RESULTS
A 5-year-old African-American girl with recurrent squamous papillomas of the right bulbar and palpebral conjunctiva was treated with multiple therapies, including excision, cryotherapy, and conjunctival injection of alpha-interferon; all therapies were followed by recurrence. After treatment with excision followed by intraoperative application of mitomycin C to the involved conjunctiva, the patient had no recurrence in a 30-month period.
CONCLUSIONS
Excision with application of mitomycin C was successful in managing a case of squamous papillomatosis that was resistant to traditional therapy.
目的
报告一种通过切除并应用丝裂霉素C治疗复发性结膜鳞状乳头状瘤的有效方法。
方法
病例报告。
结果
一名5岁非裔美国女孩，右眼球结膜和睑结膜患有复发性鳞状乳头状瘤，接受了多种治疗，包括切除、冷冻疗法和结膜注射α干扰素；所有治疗后均复发。在切除肿瘤后，术中对受累结膜应用丝裂霉素C，该患者在30个月内未复发。
结论
切除并应用丝裂霉素C成功治疗了一例对传统治疗耐药的鳞状乳头状瘤病病例。
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